I knew it!

Around age 45, I felt like my body was suddenly becoming more fragile. 😱

According to an article in Nature Aging on August 14th, 2024 by the prolific Michael Snyder and his team at Stanford University (Nonlinear dynamics of multi-omics profiles during human aging, Open Access!: lnkd.in/gnVsgQcT), two major shifts in our internal make up take place over the lifetime: molecules and microbiomes exhibit dramatic changes in nature and numbers in the mid-40s and early 60s, independent of gender.

"In people in their 40s, significant changes were seen in the number of molecules related to alcohol, caffeine and lipid metabolism; cardiovascular disease; and skin and muscle. In those in their 60s, changes were related to carbohydrate and caffeine metabolism, immune regulation, kidney function, cardiovascular disease, and skin and muscle." (lnkd.in/gUjVVfv4).

Given my experience with my mid-40s, I am not looking forward to my early 60s. Or it might be a good time to adjust lifestyle.